Hypotension and Syncope
HUGH CALKINS DOUGLAS P. ZIPES Syncope is a sudden transient loss of consciousness and postural tone with spontaneous recovery. Loss of consciousness results from a reduction of blood flow to the reticular activating system located in the brain stem and does not require electrical or chemical therapy for reversal. The metabolism of the brain, in contrast to that of many other organs, is exquisitely dependent on perfusion. Consequently, cessation of cerebral blood flow leads to loss of consciousness within approximately 10 seconds. Syncope is an important clinical problem because it is common, is costly, is often disabling, may cause injury, and may be the only warning sign before sudden cardiac death.[1] [2] [3] [4] [14A] [21A] [21B] [28A] Patients with syncope account for 1 percent of hospital admissions and 3 percent of emergency department visits.[1] Elderly persons have a 6 percent annual incidence of syncope. Surveys of young adults have revealed that up to 50 percent report a prio...